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What is known about the inheritance pattern and genetic risk factors,

Ms. D is a 41 year-old woman who presents to her primary care doctor for a routine annual exam. Her mother was diagnosed with Alzheimer’s disease a few years ago. Ms. D. is caring for her mother, which has become increasingly difficult. She is concerned about developing Alzheimer’s disease in the future.

Family History: Ms. D. is the youngest of 3 children. She works in the fashion industry and is happily married with 2 sons. Aside from having high cholesterol, she is healthy. Her parents emigrated from Russia before she was born. Her father died from a heart attack at age 68. Her mother, age 75, is currently living with Ms.D. and has Alzheimer’s disease.

Question answers should be based on evidence found in readings and from peer-reviewed literature. At least two sources must be used and cited in APA format for each question. Only one source can be a textbook. Resources should generally be within 5 years unless you are explaining the pathophysiology of a disease or providing pertinent background information

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Discussion Questions:

  1. What is known about the inheritance pattern and genetic risk factors for the development of Alzheimer’s disease?
  2. Describe the pathology of Alzheimer’s disease.
  3. Describe risk factors for development of Alzheimer’s disease and whether any are modifiable.

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