Sickle cell anemia is the result of a single mutation in the sequence of Hb. Parents who each carry the sickle cell trait (one normal Hb gene, and one with the sickle cell mutation) have a 50% chance of having a child afflicted with sickle cell anemia. Explain how the offspring would be affected, in the mother’s uterus and grown up, if s/he carried two copies of the sickle-cell Hb gene.

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Sickle cell anemia is the result of a single mutation in the sequence of Hb. Parents who each carry the sickle cell trait (one normal Hb gene, and one with the sickle cell mutation) have a 50% chance of having a child afflicted with sickle cell anemia. Explain how the offspring would be affected, in the mother’s uterus and grown up, if s/he carried two copies of the sickle-cell Hb gene.

 

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