a reaction with the enzyme and substrate

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You have an enzyme, its substrate, and a small molecule. If you perform a reaction with the enzyme and substrate, you can detect lots of product after 5 minutes. If you perform a second reaction with all three, you fail to detect product even after 30 minutes. When you further analyze your second reaction, you determine that the substrate is bound to the enzyme. Why is no product produced when the substrate can bind the enzyme?


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